Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126366 | 0.79 | L3MBTL1 (0.43) | MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL6920177 | 0.75 | NPC1 (0.40) | TDP1 | |
| SCHEMBL9900205 | 0.73 | ADRA1D (0.43) | MAPTPOLBALDH1A1ADRA1DADRA1A | |
| SCHEMBL6828965 | 0.72 | MAOB (0.40) | TDP1ALDH1A1 | |
| SCHEMBL6829285 | 0.72 | MAOB (0.44) | MAPTPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL16901841 | 0.70 | DPP4 (0.45) | MAPTALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL30762026 | 0.70 | — | — | |
| SCHEMBL8185448 | 0.70 | — | — | |
| SCHEMBL6923233 | 0.70 | ADRA1D (0.45) | MAPTTDP1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL29020313 | 0.69 | ALDH1A1 (0.44) | MAPTPOLBALDH1A1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |