Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828835 | 0.84 | LMNA (0.44) | PRSS1TMPRSS15MAPTNPC1RAB9A | |
| SCHEMBL6828740 | 0.84 | MAPT (0.41) | PRSS1TMPRSS15MAPTNPC1RAB9A | |
| SCHEMBL6828754 | 0.84 | KMT2A (0.42) | PRSS1TMPRSS15MAPTNPC1RAB9A | |
| SCHEMBL6831170 | 0.81 | MAPT (0.50) | PRSS1TMPRSS15MAPTNPC1RAB9A | |
| SCHEMBL6829103 | 0.81 | KIF11 (0.44) | PRSS1TMPRSS15MAPTALDH1A1KMT2A | |
| SCHEMBL6826064 | 0.78 | CHRNA3 (0.39) | PRSS1TMPRSS15MAPTNPC1RAB9A | |
| SCHEMBL6831122 | 0.74 | LMNA (0.50) | MAPTNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL2226671 | 0.73 | NPSR1 (0.53) | MAPTNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6829229 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL6826417 | 0.70 | MRGPRX4 (0.35) | PRSS1TMPRSS15MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |