Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.44 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.39 |
| ▸ | ITPR3 | Q14573 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897909 | 1.00 | TLR4 (0.44) | TLR4LY96LGALS8ITPR3 | |
| SCHEMBL898729 | 1.00 | TLR4 (0.44) | TLR4LY96LGALS8ITPR3 | |
| SCHEMBL15631727 | 0.88 | TLR4 (0.39) | TLR4LY96LGALS8 | |
| SCHEMBL15631754 | 0.88 | TLR4 (0.39) | TLR4LY96LGALS8 | |
| SCHEMBL15631732 | 0.88 | TLR4 (0.39) | TLR4LY96LGALS8 | |
| SCHEMBL898764 | 0.87 | FBP1 (0.46) | ITPR3 | |
| SCHEMBL898646 | 0.87 | FBP1 (0.46) | ITPR3 | |
| SCHEMBL118472 | 0.84 | LGALS8 (0.47) | LGALS8ITPR3 | |
| SCHEMBL17052655 | 0.80 | TLR4 (0.39) | TLR4LY96 | |
| SCHEMBL25976119 | 0.80 | TLR4 (0.39) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390045-A1 | THE USE OF A COMPOUND WITH A NEGATIVELY CHARGED DOMAIN OF RADICALS FOR THE TREATMENT OF RESTENOSIS | Bioneris AB, c/o Ekonomikonsult Islinge KB (SE) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002096436-A1 | THE USE OF A COMPOUND WITH A NEGATIVELY CHARGED DOMAIN OF RADICALS FOR THE TREATMENT OF RESTENOSIS | BIONERIS AB (SE) | 2002-12-05 | — | — | WO | disclosed |