SCHEMBL898729

SCHEMBL898729

CO[C@H]1O[C@H](CO)[C@@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@H]1OP(=O)(O)O

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TLR4 O00206 1/20 0.44
▸ LY96 Q9Y6Y9 1/20 0.44
▸ LGALS8 O00214 2/20 0.39
▸ ITPR3 Q14573 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829446 1.00 TLR4 (0.44) TLR4LY96LGALS8ITPR3
SCHEMBL897909 1.00 TLR4 (0.44) TLR4LY96LGALS8ITPR3
SCHEMBL15631727 0.88 TLR4 (0.39) TLR4LY96LGALS8
SCHEMBL15631754 0.88 TLR4 (0.39) TLR4LY96LGALS8
SCHEMBL15631732 0.88 TLR4 (0.39) TLR4LY96LGALS8
SCHEMBL898764 0.87 FBP1 (0.46) ITPR3
SCHEMBL898646 0.87 FBP1 (0.46) ITPR3
SCHEMBL118472 0.84 LGALS8 (0.47) LGALS8ITPR3
SCHEMBL17052655 0.80 TLR4 (0.39) TLR4LY96
SCHEMBL25976119 0.80 TLR4 (0.39) TLR4LY96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140155334-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITÉ DE STRASBOURG (FR) 2014-06-05 — — US claimed
US-20140088036-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITE DE STRASBOURG (FR) 2014-03-27 — — US claimed
US-20210361680-A1 INOSITOL-BASED IMMUNOTHERAPIES NORMOXYS INC (US) 2021-11-25 — — US disclosed
EP-3787634-A1 INOSITOL-BASED IMMUNOTHERAPIES NormOxys, Inc. (US) 2021-03-10 — — EP disclosed
US-20160067267-A1 MYO-INOSITOL TRISPYROPHOSPHATE AS AN ANTI-OBESITY AGENT NORMOXYS, INC. (US) 2016-03-10 — — US disclosed
WO-2015138916-A1 MYO-INOSITOL TRISPYROPHOSHATE AS AN ANTI-DIABETIC AGENT NICOLAU YVES CLAUDE (US) 2015-09-17 — — WO disclosed
US-20140155334-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITÉ DE STRASBOURG (FR) 2014-06-05 — — US disclosed
US-20140088036-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITE DE STRASBOURG (FR) 2014-03-27 — — US disclosed
EP-2621273-A2 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES Normoxys, Inc. (US) 2013-08-07 — — EP disclosed
WO-2012045009-A2 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES NORMOXYS, INC. (US) 2012-04-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155334-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES PPIP5K2, INPP5A, INPP5B TLR4 925/4885LY96 4436/4885LGALS8 2498/4885
US-20140088036-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES PPIP5K2, INPP5A, INPP5B TLR4 925/4885LY96 4436/4885LGALS8 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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