Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396688 | 0.86 | HTR1A (0.57) | KMT2AMEN1CCNT1CDK9HTR1A | |
| SCHEMBL27920146 | 0.75 | SIGMAR1 (0.51) | KMT2AMEN1SIGMAR1HTR1AALDH1A1 | |
| SCHEMBL10827443 | 0.75 | PTGS2 (0.45) | KMT2AMEN1HTR7DRD2ALDH1A1 | |
| SCHEMBL7884097 | 0.75 | MEN1 (0.55) | KMT2AMEN1CCNT1CDK9HTR1A | |
| SCHEMBL6179323 | 0.75 | CCNT1 (0.67) | KMT2AMEN1CCNT1CDK9HTR1A | |
| SCHEMBL10281292 | 0.74 | HTR1A (0.41) | KMT2AMEN1HTR7GFERCXCR2 | |
| Hydrochloric Acid SCHEMBL10354317 | 0.73 | DRD2 (0.49) | SIGMAR1HTR1ADRD2LMNAPOLB | |
| SCHEMBL5246497 | 0.73 | OPRM1 (0.59) | KMT2AMEN1CCNT1CDK9HTR1A | |
| SCHEMBL9047192 | 0.72 | MEN1 (0.48) | KMT2AMEN1HTR7SIGMAR1ALDH1A1 | |
| SCHEMBL9045021 | 0.72 | MEN1 (0.48) | KMT2AMEN1HTR7SIGMAR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004010943-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |