Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | SETD1B | Q9UPS6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489966 | 0.93 | BRD4 (0.37) | TDP1DRD2PPARG | |
| SCHEMBL6829609 | 0.82 | FFAR1 (0.40) | FFAR4FFAR1TDP1ALDH1A1MAPT | |
| SCHEMBL6497406 | 0.81 | BRD4 (0.41) | FFAR4FFAR1TDP1DRD2MAPT | |
| SCHEMBL6489796 | 0.80 | MAPT (0.42) | TDP1ALDH1A1MAPTMEN1NPC1 | |
| SCHEMBL6491416 | 0.74 | PPARG (0.41) | FFAR4FFAR1KDM4EALDH1A1PPARG | |
| SCHEMBL6496310 | 0.74 | THRB (0.41) | DRD2KDM4EP4HBNPSR1MEN1 | |
| SCHEMBL7070089 | 0.73 | FFAR1 (0.36) | FFAR4FFAR1TDP1KDM4EALDH1A1 | |
| SCHEMBL6492219 | 0.73 | DRD2 (0.36) | DRD2KDM4EP4HBNPSR1MAPK1 | |
| SCHEMBL6487724 | 0.72 | HDAC1 (0.39) | ALDH1A1PPARGMAPTMEN1NPC1 | |
| SCHEMBL7070085 | 0.72 | MAPT (0.36) | FFAR4FFAR1TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |