Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149243 | 0.82 | TDP1 (0.61) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL30506704 | 0.82 | TDP1 (0.61) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL4758455 | 0.76 | TDP1 (0.73) | TDP1ALDH1A1CA12CA1CA2 | |
| SCHEMBL6833259 | 0.75 | TDP1 (0.67) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL6832248 | 0.75 | TDP1 (0.67) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| Trolamine SCHEMBL29052093 | 0.74 | TDP1 (0.51) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL15341181 | 0.74 | TDP1 (0.74) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL15012772 | 0.74 | TDP1 (0.65) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL23457841 | 0.72 | TDP1 (0.67) | TDP1ALDH1A1L3MBTL1CYP3A4TSHR | |
| SCHEMBL6834883 | 0.72 | TDP1 (0.67) | TDP1ALDH1A1L3MBTL1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127737-A1 | Process for the preparation of carboxylic acid benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-01 | — | — | US | disclosed |
| US-20030233008-A1 | Process for the preparation of carboxylic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-18 | — | — | US | disclosed |
| US-6639093-B2 | Reacting benzyl chloride with hydroxybenzoic acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| US-6600064-B2 | Reacting dibenzyl ethers with alkylcarbonyloxybenzoic or alkoxycarbonyloxybenzoic acids in the presence of one or more acids as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20030055279-A1 | Process for the preparation of benzyl carboxylates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | BAYER AKTIENGESELLSCHAFT (DE) | 2003-03-20 | — | — | US | disclosed |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | LANXESS DEUTSCHLAND GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127737-A1 | Process for the preparation of carboxylic acid benzyl esters | CA4, CA7, CA9 | TDP1 4705/4885ALDH1A1 645/4885L3MBTL1 4774/4885 |
| US-20030233008-A1 | Process for the preparation of carboxylic benzyl esters | CPS1, BCAT2, BCAT1 | TDP1 4251/4885ALDH1A1 1490/4885L3MBTL1 3489/4885 |
| US-20030055279-A1 | Process for the preparation of benzyl carboxylates | GABRG2, CA4, NBAS | TDP1 4546/4885ALDH1A1 509/4885L3MBTL1 4696/4885 |
| US-20030053964-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, HACL2 | TDP1 3956/4885ALDH1A1 405/4885L3MBTL1 2479/4885 |
| US-20020128523-A1 | Process for the preparation of hydroxybenzoic benzyl esters | HAAO, HPD, ALKBH3 | TDP1 3355/4885ALDH1A1 303/4885L3MBTL1 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.