Sugi Predict

Sugi Predict / Compounds / SCHEMBL149243

SCHEMBL149243

SCHEMBL149243

CC(C)c1ccc(C(=O)OCc2ccccc2)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 3/20 0.61
▸ ALDH1A1 P00352 3/20 0.51
▸ EGFR P00533 1/20 0.48
▸ MAOB P27338 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ LMNA P02545 1/20 0.48
▸ KMT2A Q03164 2/20 0.47
▸ SLC6A2 P23975 1/20 0.47
▸ SLC6A3 Q01959 1/20 0.47
▸ CA12 O43570 1/20 0.47
▸ CA1 P00915 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ CA7 P43166 1/20 0.47
▸ CA9 Q16790 1/20 0.47
▸ CA14 Q9ULX7 1/20 0.47
▸ SERPINE1 P05121 1/20 0.45
▸ PLG P00747 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30506704 1.00 TDP1 (0.61) TDP1ALDH1A1EGFRMAOBCYP3A4
Trolamine SCHEMBL29052093 0.91 TDP1 (0.51) TDP1ALDH1A1EGFRMAOBCYP3A4
Benzyl Salicylate SCHEMBL10560506 0.86 TDP1 (0.75) TDP1ALDH1A1EGFRCYP3A4TSHR
SCHEMBL10890743 0.84 EGFR (0.61) TDP1EGFRCYP3A4KMT2ACA12
SCHEMBL29611559 0.83 TDP1 (0.69) TDP1ALDH1A1EGFRCYP3A4TSHR
SCHEMBL39675 0.83 TDP1 (0.69) TDP1ALDH1A1EGFRCYP3A4TSHR
SCHEMBL6829708 0.82 TDP1 (0.53) TDP1ALDH1A1EGFRMAOBCYP3A4
SCHEMBL4758455 0.82 TDP1 (0.73) TDP1ALDH1A1EGFRLMNAKMT2A
SCHEMBL6832248 0.81 TDP1 (0.67) TDP1ALDH1A1MAOBCYP3A4TSHR
SCHEMBL1648346 0.81 HTT (0.50) TDP1ALDH1A1CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 461 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999512-A PC material and preparation method and application thereof 上海中镭新材料科技有限公司 2022-02-01 — — CN claimed
CN-111019315-B Glass fiber reinforced PC material and preparation method and application thereof 上海中镭新材料科技有限公司 2021-12-31 — — CN claimed
CN-110982240-B polycarbonate/ABS (acrylonitrile-butadiene-styrene) composition, preparation method and automobile column guard plate 上海中镭新材料科技有限公司 2021-12-10 — — CN claimed
WO-2021128964-A1 ELECTROPLATED NYLON MATERIAL AND PREPARATION METHOD THEREOF 上海中镭新材料科技有限公司 2021-07-01 — — WO claimed
CN-112759914-A Compound halogen-free flame-retardant engineering resin and preparation method and application thereof 上海中镭新材料科技有限公司 2021-05-07 — — CN claimed
CN-112322019-A High-hardness transparent flame-retardant PC material and preparation method thereof 上海艰卓科技有限公司 2021-02-05 — — CN claimed
US-20190099342-A1 COOLING PRODUCT SYMRISE AG (DE) 2019-04-04 — — US claimed
WO-2007110415-A2 USE OF DIACETYL TRIMERS AND COSMETIC OR THERAPEUTIC FORMULATIONS CONTAINING THESE COMPOUNDS SYMRISE GMBH & CO. KG (DE) 2007-10-04 — — WO claimed
US-6468509-B2 Sunscreen composition containing sol-gel microcapsules SOL-GEL TECHNOLOGIES LTD. (IL) 2002-10-22 — — US claimed
US-20020037261-A1 Sunscreen composition containing sol-gel microcapsules LAPIDOT NAO (IL) 2002-03-28 — — US claimed
US-20240237643-A1 COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY SYMRISE AG (DE) 2024-07-18 — — US disclosed
US-20240216248-A1 MICROBIAL GLYCOLIPIDS ANALYTICON DISCOVERY GMBH (DE) 2024-07-04 — — US disclosed
US-12023396-B2 Flavour and fragrance compositions comprising acetophenone derivatives SYMRISE AG (DE) 2024-07-02 — — US disclosed
US-12016944-B2 Mixtures comprising a protein extract for the treatment of human skin and/or hair SYMRISE AG (DE) 2024-06-25 — — US disclosed
US-20240122816-A1 ARTICLES FOR INDIRECT TRANSFER OF COSMETIC ACTIVES TO SKIN SYMRISE AG (DE) 2024-04-18 — — US disclosed
CN-1273088-A Use of amino-substituted hydroxybenzophenones as photostable UV filters in cosmetic and pharmaceutical preparations BASF AG (DE) 2000-11-15 — — CN disclosed
CN-1267213-A Use of bis (resorcinyl) triazine derivatives in cosmetics CIBA SC HOLDING AG (CH) 2000-09-20 — — CN disclosed
CN-1229636-A Cosmetic and pharmaceutical preparations containing photostable UV filters BASF AG (DE) 1999-09-29 — — CN disclosed
CN-1224032-A Use of isoindolinone derivatives as stabilizers for organic materials BASF AG (DE) 1999-07-28 — — CN disclosed
EP-0786246-A1 Cosmetic and dermatological sunscreen formulations containing triazine derivatives and glycerylcompounds Beiersdorf Aktiengesellschaft (DE) 1997-07-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190099342-A1 COOLING PRODUCT TRPA1, TRPV2, NISCH TDP1 880/4885ALDH1A1 40/4885EGFR 4431/4885
US-12023396-B2 Flavour and fragrance compositions comprising acetophenone derivatives FAAH2, ADH5, NISCH TDP1 4138/4885ALDH1A1 54/4885EGFR 4095/4885
US-20240216248-A1 MICROBIAL GLYCOLIPIDS UGCG, SGMS1, GPR119 TDP1 4625/4885ALDH1A1 1617/4885EGFR 1565/4885
US-20240122816-A1 ARTICLES FOR INDIRECT TRANSFER OF COSMETIC ACTIVES TO SKIN CUTA, POLR1C, SLC16A7 TDP1 2965/4885ALDH1A1 938/4885EGFR 2373/4885
US-20240237643-A1 COMPOSITIONS WITH VIRUCIDAL AND/OR ANTIVIRAL ACTIVITY ZC3HAV1, SAMHD1, ZC3HAV1L TDP1 810/4885ALDH1A1 1969/4885EGFR 4429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.