Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830910 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HSD17B10MAPK1HPGDTSHR | |
| SCHEMBL6829307 | 0.85 | ADORA2A (0.41) | ALDH1A1HSD17B10MAPK1HPGDXIAP | |
| SCHEMBL6825783 | 0.83 | ADORA1 (0.56) | ALDH1A1HSD17B10MAPK1HPGDTSHR | |
| SCHEMBL6828830 | 0.83 | ADORA2A (0.48) | ALDH1A1HSD17B10MAPK1HPGDTSHR | |
| SCHEMBL6828434 | 0.81 | HDAC1 (0.44) | ALDH1A1XIAPADORA2AADORA1MAPT | |
| SCHEMBL6828505 | 0.81 | ADORA2A (0.54) | ALDH1A1ADORA2AADORA1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6828629 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10MAPK1HPGDXIAP | |
| SCHEMBL6828729 | 0.80 | ADORA1 (0.57) | ALDH1A1ADORA2AADORA1MAPTKMT2A | |
| SCHEMBL6828997 | 0.80 | ADORA3 (0.49) | ALDH1A1HSD17B10HPGDXIAPADORA2A | |
| SCHEMBL6829128 | 0.79 | ADORA2A (0.41) | ALDH1A1XIAPADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441732-A2 | THIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003039451-A2 | THIAZOLE PYRIDAZINONES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-15 | — | — | WO | disclosed |