Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.40 |
| ▸ | FNTB | P49356 | 5/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CLPP | Q16740 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417962 | 0.88 | BCL2L1 (0.38) | FNTAPGGT1BFNTBKCNA5TDP1 | |
| SCHEMBL6832903 | 0.85 | KCNA5 (0.39) | FNTAPGGT1BFNTBKCNA5CLPP | |
| SCHEMBL6830895 | 0.75 | CASP3 (0.43) | FNTAPGGT1BFNTBKCNA5CLPP | |
| SCHEMBL7418208 | 0.73 | LMNA (0.52) | TDP1CASP3CASP6CASP8 | |
| SCHEMBL7204618 | 0.71 | CASP3 (0.59) | CLPPCASP3CASP6CASP8 | |
| SCHEMBL6832902 | 0.67 | MME (0.39) | FNTAPGGT1BFNTBKCNA5CLPP | |
| SCHEMBL27544012 | 0.67 | ALDH1A1 (0.42) | TDP1ACE | |
| SCHEMBL7201963 | 0.64 | CASP3 (0.48) | CLPPMMEACECPA1ACE2 | |
| SCHEMBL7201964 | 0.64 | CASP3 (0.48) | CLPPMMEACECPA1ACE2 | |
| SCHEMBL7361590 | 0.64 | ALDH1A1 (0.50) | FNTAFNTBMMP1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480999-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072528-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |