Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPX4 | P36969 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834284 | 0.92 | ALDH1A1 (0.35) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL18022224 | 0.78 | GPX4 (0.32) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL13559239 | 0.77 | GPX4 (0.31) | GPX4KDM4ENPC1POLBMAPT | |
| SCHEMBL16737003 | 0.76 | GPX4 (0.34) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL6834114 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL304319 | 0.74 | GPX4 (0.33) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL3809880 | 0.73 | GPX4 (0.33) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL75010 | 0.72 | GPX4 (0.34) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL18400928 | 0.72 | GPX4 (0.34) | ALDH1A1GPX4KDM4ENPC1POLB | |
| SCHEMBL3803250 | 0.71 | GPX4 (0.33) | ALDH1A1GPX4KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746818-B2 | (METH)ACRYLATE COMPOUNDS HAVING A NORBORNANE, BICYCLO(2.2.2) OCTANE, 7-OXANORBORNANE OR CYCLOHEXANE RING STRUCTURE AND A GAMMA-BUTYROLACTONE RING STRUCTURE CONNECTED TOGETHER BY A LINKER, USEFUL IN FORMING POLYMER WITH HIGH TRANSPARENCY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20030008232-A1 | Novel (meth) acrylates having lactone structure, polymers, photoresist compositions and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008232-A1 | Novel (meth) acrylates having lactone structure, polymers, photoresist compositions and patterning process | MMAB, MBTD1, STK17A | ALDH1A1 1130/4885GPX4 4663/4885KDM4E 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.