Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 2/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687585 | 0.82 | ALDH1A1 (0.40) | TLR8 | |
| SCHEMBL8692203 | 0.79 | MAPT (0.37) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8689288 | 0.78 | MEN1 (0.38) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8692199 | 0.75 | MAPT (0.34) | TLR8CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL8686884 | 0.75 | NUDT1 (0.54) | — | |
| SCHEMBL8692425 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL8692276 | 0.71 | NUDT1 (0.50) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6832705 | 0.69 | CDK1 (0.40) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6834942 | 0.69 | CDK2 (0.42) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6403682 | 0.67 | ALDH1A1 (0.41) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463483-A1 | NEW COMPOSITION | Ponsus Pharma AB (SE) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003055454-A1 | NEW COMPOSITION | PONSUS PHARMA AB (SE) | 2003-07-10 | — | — | WO | disclosed |