Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL233972 | 0.79 | ACHE (0.36) | MEN1POLBKMT2A | |
| SCHEMBL1644170 | 0.78 | ACHE (0.38) | MEN1KMT2A | |
| SCHEMBL5140658 | 0.77 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL3409063 | 0.76 | ACHE (0.36) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL843038 | 0.75 | CHRM5 (0.36) | MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL28195490 | 0.74 | RAB9A (0.35) | MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL444004 | 0.74 | RAB9A (0.35) | MEN1POLBKMT2A | |
| SCHEMBL10660435 | 0.73 | LMNA (0.35) | KMT2A | |
| Hydrochloric Acid SCHEMBL6112585 | 0.73 | KMT2A (0.34) | MEN1POLBKMT2A | |
| SCHEMBL9176002 | 0.72 | BRD4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040038402-A1 | Cassette increasing persistence of a transfected eukaryotic cell expressing a gene of interest, especially muscle cell | TRANSGENE S.A. (FR) | 2004-02-26 | — | — | US | disclosed |