Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25408093 | 0.89 | MAOB (0.55) | ALDH1A1MAOBMAPTTARBP2KDM4E | |
| SCHEMBL31435424 | 0.89 | MAOB (0.55) | ALDH1A1MAOBMAPTTARBP2KDM4E | |
| SCHEMBL492496 | 0.84 | AKR1B1 (0.54) | ALDH1A1KMT2AMAOBMAPTKDM4E | |
| SCHEMBL11793990 | 0.84 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTKDM4EHPGD | |
| SCHEMBL492231 | 0.83 | TBK1 (0.48) | ALDH1A1MAPTTARBP2KDM4EELANE | |
| SCHEMBL8226588 | 0.83 | HTT (0.50) | ALDH1A1MAPTKDM4EELANESMN1; SMN2 | |
| SCHEMBL14492918 | 0.83 | KDM4E (0.42) | ALDH1A1KMT2ATARBP2KDM4E | |
| SCHEMBL492601 | 0.83 | LMNA (0.46) | ALDH1A1KMT2AMAPTKDM4EALOX15 | |
| SCHEMBL491943 | 0.82 | KDM4E (0.50) | ALDH1A1KMT2AMAOBMAPTTARBP2 | |
| SCHEMBL2815397 | 0.80 | ESR1 (0.44) | ALDH1A1KMT2ATARBP2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ALDH1A1 170/4885KMT2A 2853/4885MAOB 1623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.