Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834280 | 0.81 | NR1H4 (0.54) | SMN1; SMN2NPC1RAB9AKDM4ENPSR1 | |
| SCHEMBL6833082 | 0.80 | JAK2 (0.44) | PKMNPC1RAB9ANPSR1PRSS12 | |
| SCHEMBL6830407 | 0.79 | MEN1 (0.71) | SMN1; SMN2PKMNPC1KDM4EMAPK1 | |
| SCHEMBL2275537 | 0.78 | HDAC1 (0.78) | SMN1; SMN2PKMNPC1NFKB1RAB9A | |
| SCHEMBL2273799 | 0.77 | HDAC1 (0.73) | SMN1; SMN2PKMNPC1NFKB1RAB9A | |
| SCHEMBL6833642 | 0.77 | RAB9A (0.67) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL6353963 | 0.77 | KMT2A (0.62) | PKMMEN1KMT2AMAPTHTT | |
| SCHEMBL6348609 | 0.76 | KMT2A (0.44) | PKMNPC1RAB9ATHRBKDM4E | |
| SCHEMBL6834585 | 0.75 | LMNA (0.47) | SMN1; SMN2NPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL6348677 | 0.75 | SERPINE1 (0.66) | PKMNPC1RAB9AKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | SMN1; SMN2 2022/4885PKM 3785/4885NPC1 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.