SCHEMBL6834548

SCHEMBL6834548

Cc1noc(C)c1-c1ccc2cc(C(=O)Nc3ccc(C#N)cc3C(=O)O)n(C)c2c1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 5/20 0.41
FTO Q9C0B1 5/20 0.40
HCAR2 Q8TDS4 1/20 0.40
ALB P02768 3/20 0.38
CREBBP Q92793 1/20 0.37
LCK P06239 1/20 0.37
FYN P06241 1/20 0.37
P2RY14 Q15391 1/20 0.36
BRD2 P25440 1/20 0.36
BRD3 Q15059 1/20 0.36
PRSS12 P56730 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
EP300 Q09472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6710311 0.83 FTO (0.41) BRD4FTOCREBBPLCKFYN
SCHEMBL6713399 0.83 BRD4 (0.37) BRD4CREBBPLCKFYNBRD2
SCHEMBL7071019 0.82 ALDH1A1 (0.44) ALBLMNATP53MAPT
SCHEMBL6833879 0.81 LMNA (0.43) ALBLCKPRSS12LMNATP53
SCHEMBL6833857 0.80 FTO (0.41) BRD4FTOHCAR2ALBP2RY14
SCHEMBL6835707 0.78 ALB (0.41) ALBLMNATP53MAPT
SCHEMBL6818878 0.78 ALB (0.56) ALBLCKLMNATP53MAPT
SCHEMBL6835702 0.77 MAPT (0.47) ALBLMNATP53MAPT
SCHEMBL6818253 0.77 ROCK2 (0.42) ALBLMNATP53MAPT
SCHEMBL6833214 0.77 KCNH2 (0.47) BRD4FTOHCAR2ALBP2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110802-A1 Antibacterial benzoic acid derivatives PHARMACIA & UPJOHN COMPANY 2004-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110802-A1 Antibacterial benzoic acid derivatives GABRD, GABBR1, GABRA1 BRD4 1157/4885FTO 918/4885HCAR2 344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.