Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839675 | 0.90 | ALDH1A1 (0.50) | MMP8CYP4F2CYP4A11THRBPLK1 | |
| SCHEMBL6839732 | 0.87 | CYSLTR2 (0.51) | THRBKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL271585 | 0.87 | MMP8 (0.59) | MMP8KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7619857 | 0.86 | MMP8 (0.46) | MMP8CYP4F2CYP4A11THRBF2 | |
| SCHEMBL6839623 | 0.85 | MMP8 (0.51) | MMP8PLK1L3MBTL1KMT2AMEN1 | |
| SCHEMBL12315605 | 0.84 | PTGS2 (0.48) | CYP4F2CYP4A11THRBACACBACACA | |
| SCHEMBL11623145 | 0.82 | MMP8 (0.49) | MMP8CYP4F2CYP4A11L3MBTL1KMT2A | |
| SCHEMBL27354703 | 0.82 | MMP8 (0.49) | MMP8F2F10KMT2AMEN1 | |
| SCHEMBL4068942 | 0.81 | MMP8 (0.54) | MMP8KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL9391853 | 0.81 | POLB (0.49) | MMP8CYP4F2CYP4A11KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394272-B2 | 1,3-dioxane compound having fluorine atom in axial position, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-9394272-B2 | 1,3-dioxane compound having fluorine atom in axial position, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-20150368225-A1 | 1,3-DIOXANE COMPOUND HAVING FLUORINE ATOM IN AXIAL POSITION, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| US-20150368225-A1 | 1,3-DIOXANE COMPOUND HAVING FLUORINE ATOM IN AXIAL POSITION, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| US-6759103-B2 | NEMATIC, CHOLESTERIC OR CHIRAL SMECTIC LIQUID-CRYSTAL MIXTURES HAVING HIGH ABSOLUTE DIELECTRIC ANISOTROPY VALUES AND WITH A FAVORABLE VISCOSITY/CLEARING POINT RELATIONSHIP; PHOTOSTABILITY; HEAT AND ULTRAVIOLET RADIATION RESISTANCE | CLARIANT FINANCI (BVI) LIMITED (VG) | 2004-07-06 | — | — | US | disclosed |
| US-20030091756-A1 | Nematic, cholesteric or chiral smectic liquid-crystal mixtures having high absolute dielectric anisotropy values and with a favorable viscosity/clearing point relationship; photostability; heat and ultraviolet radiation resistance | CLARIANT INTERNATIONAL LTD. | 2003-05-15 | — | — | US | disclosed |
| US-4676924-A | Liquid crystalline isothiocyanates with dioxane ring and liquid crystalline admixtures containing same | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 1987-06-30 | — | — | US | disclosed |
| EP-0170082-A2 | Liquid crystalline isothiocyanates with a dioxane ring and liquid crystalline admixtures containing the same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1986-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368225-A1 | 1,3-DIOXANE COMPOUND HAVING FLUORINE ATOM IN AXIAL POSITION, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CXCR1, HAX1, RCC1 | MMP8 1915/4885CYP4F2 584/4885CYP4A11 1024/4885 |
| US-20030091756-A1 | Nematic, cholesteric or chiral smectic liquid-crystal mixtures having high absolute dielectric anisotropy values and with a favorable viscosity/clearing point relationship; photostability; heat and ultraviolet radiation resistance | SCO2, CNOT1, HCFC1 | MMP8 3654/4885CYP4F2 285/4885CYP4A11 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.