Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843453 | 0.90 | CA12 (0.40) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL6843437 | 0.89 | CA1 (0.48) | — | |
| SCHEMBL6842988 | 0.89 | CA1 (0.38) | ALDH1A1TSHRKMT2AMEN1MAPT | |
| SCHEMBL6843114 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TSHRKMT2AMAPK1POLB | |
| SCHEMBL6843319 | 0.85 | SRD5A2 (0.43) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6195785 | 0.85 | LMNA (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6843225 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2APOLBMEN1 | |
| SCHEMBL6211990 | 0.84 | PTPN5 (0.47) | ALDH1A1KMT2APOLBMEN1TAS2R14 | |
| SCHEMBL6838144 | 0.83 | NR4A2 (0.43) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL6843440 | 0.83 | RXRA (0.43) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | ALDH1A1 1588/4885TSHR 3787/4885KMT2A 4149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.