Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137730 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2LMNA | |
| SCHEMBL6137729 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2LMNA | |
| SCHEMBL2166669 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAMAOAMAOB | |
| SCHEMBL16628829 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAMAOAMAOB | |
| SCHEMBL16628828 | 0.74 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2LMNAMAOAMAOB | |
| SCHEMBL6336127 | 0.70 | ALDH1A1 (0.46) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2LMNA | |
| SCHEMBL6328556 | 0.70 | PTPN1 (0.41) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2LMNA | |
| SCHEMBL6138886 | 0.70 | PTPN1 (0.41) | ALDH1A1HSP90AA1HSP90AB1SMN1; SMN2LMNA | |
| SCHEMBL1960493 | 0.68 | — | — | |
| SCHEMBL2166602 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177226-B1 | Hydroxamate compositions | COVIDIEN LP (US) | 2013-09-18 | — | — | EP | disclosed |
| US-8425972-B2 | Antimicrobial materials and coatings | COVIDIEN LP (US) | 2013-04-23 | — | — | US | disclosed |
| US-8425972-B2 | Antimicrobial materials and coatings | COVIDIEN LP (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2564859-A1 | Hydroxamate compositions | Covidien LP (US) | 2013-03-06 | — | — | EP | disclosed |
| US-8153741-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153741-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110280824-A1 | Furanone Copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110280824-A1 | Furanone Copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-11-17 | — | — | US | disclosed |
| US-7999051-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-08-16 | — | — | US | disclosed |
| US-7999051-B2 | Furanone copolymers | TYCO HEALTHCARE GROUP LP (US) | 2011-08-16 | — | — | US | disclosed |
| US-7923439-B2 | Hydroxamate compositions | TYCO HEALTHCARE GROUP LP (US) | 2011-04-12 | — | — | US | disclosed |
| US-7923439-B2 | Hydroxamate compositions | TYCO HEALTHCARE GROUP LP (US) | 2011-04-12 | — | — | US | disclosed |
| US-20100130713-A1 | FURANONE COPOLYMERS | COVIDIEN LP | 2010-05-27 | — | — | US | disclosed |
| US-20100130713-A1 | FURANONE COPOLYMERS | COVIDIEN LP | 2010-05-27 | — | — | US | disclosed |
| US-20100119695-A1 | ANTIMICROBIAL MATERIALS AND COATINGS | COVIDIEN LP | 2010-05-13 | — | — | US | disclosed |
| US-20100119695-A1 | ANTIMICROBIAL MATERIALS AND COATINGS | COVIDIEN LP | 2010-05-13 | — | — | US | disclosed |
| US-20100093846-A1 | HYDROXAMATE COMPOSITIONS | TYCO HEALTHCARE GROUP LP | 2010-04-15 | — | — | US | disclosed |
| US-20100093846-A1 | HYDROXAMATE COMPOSITIONS | TYCO HEALTHCARE GROUP LP | 2010-04-15 | — | — | US | disclosed |
| WO-2008144247-A1 | ANTIMICROBIAL MATERIALS AND COATINGS | TYCO HEALTHCARE GROUP LP (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008144248-A1 | FURANONE COPOLYMERS | TYCO HEALTHCARE GROUP LP (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110280824-A1 | Furanone Copolymers | PLA2G5, PLA2G2A, PLA2G10 | ALDH1A1 1402/4885HSP90AA1 3616/4885HSP90AB1 4093/4885 |
| US-20100093846-A1 | HYDROXAMATE COMPOSITIONS | HCAR3, ABHD16A, PLA2G2C | ALDH1A1 1297/4885HSP90AA1 762/4885HSP90AB1 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.