Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843203 | 0.87 | MMP13 (0.40) | MMP13LOXL2GRM2PIM1 | |
| SCHEMBL6843067 | 0.87 | MMP13 (0.39) | MMP13LOXL2GRM2 | |
| SCHEMBL7104741 | 0.85 | KMT2A (0.43) | PIM1 | |
| SCHEMBL6211286 | 0.85 | LOXL2 (0.40) | MMP13LOXL2GRM2 | |
| SCHEMBL6844668 | 0.84 | NPC1 (0.49) | — | |
| SCHEMBL6843459 | 0.84 | MMP13 (0.52) | MMP13 | |
| SCHEMBL6843418 | 0.84 | SRD5A2 (0.45) | PIM1 | |
| SCHEMBL6843351 | 0.83 | GRM2 (0.41) | MMP13LOXL2GRM2 | |
| SCHEMBL6845458 | 0.83 | THRB (0.45) | MMP13 | |
| SCHEMBL6843224 | 0.82 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | MMP13 3/4885LOXL2 1024/4885GRM2 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.