Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055100 | 0.93 | KDM4E (0.50) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL13620753 | 0.85 | ADRB1 (0.74) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL6055386 | 0.85 | ACHE (0.48) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL1812811 | 0.84 | SLC6A2 (0.51) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL13626474 | 0.84 | ADRA1A (0.46) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL28951519 | 0.84 | ACP3 (0.46) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL9667227 | 0.84 | CES2 (0.50) | ADRA1AHTR2AADRB1MIFHTR2B | |
| SCHEMBL1961679 | 0.83 | KDM4E (0.65) | ADRA1AHTR2AKDM4EHIF1ALMNA | |
| SCHEMBL765762 | 0.83 | KDM4E (0.65) | ADRA1AHTR2AKDM4EHIF1ALMNA | |
| SCHEMBL28263575 | 0.83 | KDM4E (0.65) | ADRA1AHTR2AKDM4EHIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116619-A1 | Polyester resins with improved properties | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2004-06-17 | — | — | US | claimed |
| US-20040116619-A1 | Polyester resins with improved properties | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2004-06-17 | — | — | US | disclosed |
| EP-0089781-B1 | BICYCLIC BENZO FUSED COMPOUNDS | PFIZER INC. (US) | 1990-08-08 | — | — | EP | disclosed |
| US-4870084-A | ANALGESICS, ANTIDIARRHEALS | PFIZER INC. (US) | 1989-09-26 | — | — | US | disclosed |
| US-4863934-A | Bicyclic benzo fused pyran compounds used for producing analgesia | PFIZER INC. (US) | 1989-09-05 | — | — | US | disclosed |
| US-4841078-A | ANALGESICS | PFIZER INC. (US) | 1989-06-20 | — | — | US | disclosed |
| US-4680404-A | ANALGESICS, TRANQUILIZERS, ANTIEMETICS, DIURETICS, ANTICONVULSANTS | PFIZER INC. (US) | 1987-07-14 | — | — | US | disclosed |
| US-4486428-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0089781-A2 | Bicyclic benzo fused compounds | PFIZER INC. (US) | 1983-09-28 | — | — | EP | disclosed |