SCHEMBL684389

SCHEMBL684389

CC(=O)OC[C@H](N)C(=O)N[C@@H](Cc1ccc(OC(C)=O)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
MME P08473 10/20 0.45
ACE P12821 10/20 0.45
CPA1 P15085 10/20 0.45
ACE2 Q9BYF1 10/20 0.45
PPARG P37231 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
CA2 P00918 1/20 0.42
OPRK1 P41145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12053134 1.00 ITGB3 (0.46) ITGB3ITGA2BMMEACECPA1
SCHEMBL2336902 0.92 OPRK1 (0.44) ITGB3ITGA2BMMEACECPA1
SCHEMBL9980756 0.83 SLC7A5 (0.51) ITGB3ITGA2BPPARGPOLBKMT2A
SCHEMBL12035152 0.83 POLB (0.42) ITGB3ITGA2BPPARGPOLBKMT2A
SCHEMBL20489338 0.83 ITGB3 (0.57) ITGB3ITGA2B
SCHEMBL15303130 0.81 ITGB3 (0.52) ITGB3ITGA2BMMEACECPA1
SCHEMBL9337698 0.81 ITGB3 (0.62) ITGB3ITGA2BMMEACECPA1
SCHEMBL11183676 0.81 ITGB3 (0.62) ITGB3ITGA2BMMEACECPA1
SCHEMBL8477239 0.81 ITGB3 (0.62) ITGB3ITGA2BMMEACECPA1
SCHEMBL13385726 0.80 CA2 (0.58) ITGB3ITGA2BMMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US disclosed
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US disclosed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US disclosed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US disclosed
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS SIGNATURE R&D HOLDINGS, LLC (US) 2011-12-22 US disclosed
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-11-10 US disclosed
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-11-10 US disclosed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US disclosed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US disclosed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US disclosed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA ITGB3 45/4885ITGA2B 104/4885MME 2430/4885
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS PLTP, GP6, PDGFA ITGB3 45/4885ITGA2B 104/4885MME 2430/4885
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements PLTP, GP6, PDGFA ITGB3 45/4885ITGA2B 104/4885MME 2430/4885
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA ITGB3 45/4885ITGA2B 104/4885MME 2430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.