Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844855 | 0.84 | TSHR (0.32) | CA1CA2ALDH1A1HSD17B10CA12 | |
| SCHEMBL6844881 | 0.82 | CA1 (0.38) | CA1CA2NQO2ALDH1A1TP53 | |
| SCHEMBL6844858 | 0.81 | TSHR (0.34) | CA2ALDH1A1HTTHSD17B10CA12 | |
| SCHEMBL6844920 | 0.81 | ELANE (0.34) | CA1CA2NQO2ALDH1A1TP53 | |
| SCHEMBL1648514 | 0.77 | MALT1 (0.42) | MALT1CA1CA2METAP2BCHE | |
| SCHEMBL6844879 | 0.75 | POLB (0.36) | ALDH1A1MAPTHTT | |
| SCHEMBL6844910 | 0.72 | HTR6 (0.32) | ALDH1A1HSD17B10 | |
| SCHEMBL6844919 | 0.71 | POLB (0.34) | BCHEALDH1A1MAPTHPGDRORC | |
| SCHEMBL1648523 | 0.71 | CA1 (0.47) | MALT1CA1CA2METAP2NQO2 | |
| SCHEMBL1649273 | 0.70 | MALT1 (0.39) | MALT1CA1CA2METAP2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |