Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844879 | 0.85 | POLB (0.36) | POLBKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL1648201 | 0.81 | POLB (0.38) | POLBKMT2AALDH1A1L3MBTL1MAPT | |
| SCHEMBL6844927 | 0.81 | TARBP2 (0.32) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL6844872 | 0.80 | CA1 (0.36) | POLBALDH1A1 | |
| SCHEMBL6844920 | 0.78 | ELANE (0.34) | POLBKMT2AALDH1A1HPGDMAPT | |
| SCHEMBL6844858 | 0.78 | TSHR (0.34) | POLBKMT2AALDH1A1LMNACYP2D6 | |
| SCHEMBL6844881 | 0.76 | CA1 (0.38) | ALDH1A1HPGDMAPTRORCELANE | |
| SCHEMBL1648283 | 0.75 | METAP2 (0.41) | POLBKMT2AMAPTPKMRORC | |
| SCHEMBL6844851 | 0.74 | ALDH1A1 (0.32) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL6844867 | 0.74 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |