Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844855 | 0.82 | TSHR (0.32) | HTR6TSHRHSD17B10ALDH1A1 | |
| SCHEMBL6844858 | 0.79 | TSHR (0.34) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6844881 | 0.75 | CA1 (0.38) | HSD17B10ALDH1A1 | |
| SCHEMBL6844851 | 0.73 | ALDH1A1 (0.32) | HTR6ALDH1A1 | |
| SCHEMBL14725681 | 0.73 | NAT1 (0.35) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6844879 | 0.72 | POLB (0.36) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1648037 | 0.72 | NAT1 (0.34) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6844867 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL6844920 | 0.70 | ELANE (0.34) | TSHRHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL6844919 | 0.70 | POLB (0.34) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |