Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844858 | 0.91 | TSHR (0.34) | POLBLMNACYP2D6ALDH1A1KMT2A | |
| SCHEMBL6844919 | 0.85 | POLB (0.34) | POLBLMNACYP2D6ALDH1A1MAPT | |
| SCHEMBL6844927 | 0.80 | TARBP2 (0.32) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6844920 | 0.80 | ELANE (0.34) | POLBLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL6844855 | 0.78 | TSHR (0.32) | CYP2D6ALDH1A1 | |
| SCHEMBL6844881 | 0.77 | CA1 (0.38) | ALDH1A1MAPTHTT | |
| SCHEMBL6844872 | 0.76 | CA1 (0.36) | POLBALDH1A1ALOX12HTT | |
| SCHEMBL6844851 | 0.75 | ALDH1A1 (0.32) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL6844910 | 0.72 | HTR6 (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL1648197 | 0.72 | METAP2 (0.38) | POLBKMT2AHSP90AA1KDM4EKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |