Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844872 | 0.91 | CA1 (0.36) | — | |
| SCHEMBL6844851 | 0.85 | ALDH1A1 (0.32) | METAP2 | |
| SCHEMBL6844897 | 0.82 | METAP2 (0.39) | METAP2 | |
| SCHEMBL6844864 | 0.79 | QRFPR (0.36) | — | |
| SCHEMBL6844927 | 0.76 | TARBP2 (0.32) | — | |
| SCHEMBL6844870 | 0.74 | EGFR (0.38) | METAP2 | |
| SCHEMBL6844919 | 0.74 | POLB (0.34) | — | |
| SCHEMBL1649148 | 0.73 | METAP2 (0.48) | METAP2 | |
| SCHEMBL6844858 | 0.73 | TSHR (0.34) | TSHR | |
| SCHEMBL1648275 | 0.71 | KMT2A (0.39) | TSHRMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044506-A2 | SULPHONE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ZAFGEN CORPORATION (US) | 2011-04-14 | — | — | WO | disclosed |