Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846105 | 0.84 | MAPK14 (0.49) | CDC7CDK2CYP3A4CYP1A2HSD17B10 | |
| SCHEMBL6847772 | 0.82 | DYRK1A (0.47) | CYP3A4CYP1A2HSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL6844416 | 0.81 | CDC7 (0.41) | CDC7CDK2IMPDH2CYP3A4CYP1A2 | |
| SCHEMBL6657827 | 0.79 | CYP17A1 (0.41) | CYP3A4CYP1A2HSD17B10CYP2A6MAPK14 | |
| SCHEMBL6846191 | 0.79 | DHPS (0.50) | CYP3A4CYP1A2ALDH1A1CYP2A6MAPK14 | |
| SCHEMBL6844276 | 0.77 | CDC7 (0.44) | CDC7CYP1A2ALDH1A1MAPK14MAPT | |
| SCHEMBL6844275 | 0.76 | QPCT (0.46) | CYP3A4CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL6846026 | 0.76 | KIF11 (0.48) | CYP3A4MEN1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL6846183 | 0.75 | HSD11B1 (0.45) | CDC7CDK2CYP3A4CYP1A2HSD17B10 | |
| SCHEMBL6657706 | 0.74 | CYP11B2 (0.43) | CYP3A4CYP1A2HSD17B10CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | CDC7 1627/4885CDK2 732/4885IMPDH2 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.