Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236030 | 1.00 | FAAH (0.54) | FAAHNOD1ITGB3ITGA2BMMP2 | |
| SCHEMBL8241705 | 0.89 | MEN1 (0.51) | TACR1 | |
| SCHEMBL8426548 | 0.86 | OPRM1 (0.48) | FAAHMMP2MMP9MMP8ALDH1A1 | |
| SCHEMBL8427674 | 0.85 | CERT1 (0.46) | MMP2MMP9MMP8ALDH1A1ASAH1 | |
| SCHEMBL8242363 | 0.84 | TACR1 (0.48) | FAAHMMP2MMP9MMP8CTSL | |
| SCHEMBL8427676 | 0.83 | ALDH1A1 (0.42) | FAAHMMP2MMP9MMP8CTSL | |
| SCHEMBL8244970 | 0.83 | CTSL (0.43) | MMP2MMP9MMP8CTSLCTSS | |
| SCHEMBL3662267 | 0.81 | FAAH (0.58) | FAAHNOD1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL3660631 | 0.81 | FAAH (0.58) | FAAHNOD1ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8672727 | 0.81 | FAAH (0.58) | FAAHNOD1ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767718-B2 | CYCLODEPSIPEPTIDE INTERMEDIATES USED TO SYNTHESIZE NEW LIPODEPSIPEPTIDE ; ANTIBIOTICS; HAVE ANTIBACTERIAL ACTIVITY AGAINST GRAM POSITIVE BACTERIA; LESS TOXIC THAN ANTIBIOTIC DAPTOMYCIN | BIOSOURCE PHARM, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20030224475-A1 | Lipodepsipeptide antibiotics and methods of preparation | BIOSOURCE PHARM, INC. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030224475-A1 | Lipodepsipeptide antibiotics and methods of preparation | NPEPPS, MRPL38, LYPLA2 | FAAH 1480/4885NOD1 1076/4885ITGB3 4822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.