Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849683 | 0.86 | P2RX7 (0.39) | LMNAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31554993 | 0.83 | MEN1 (0.34) | POLBMEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL30580590 | 0.64 | MAPT (0.39) | LMNARAB9APOLBMEN1KMT2A | |
| SCHEMBL7707848 | 0.61 | CNR2 (0.65) | LMNAPOLBMAPTALDH1A1NPSR1 | |
| SCHEMBL12585073 | 0.60 | ALDH1A1 (0.40) | LMNARAB9APOLBMAPTALDH1A1 | |
| SCHEMBL5295731 | 0.60 | LMNA (0.63) | LMNARAB9APOLBMEN1KMT2A | |
| SCHEMBL5923504 | 0.59 | P2RX7 (0.73) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL171236 | 0.59 | POLB (0.47) | LMNARAB9APOLBMEN1KMT2A | |
| SCHEMBL7976984 | 0.59 | RAB9A (0.43) | LMNARAB9APOLBNPC1MAPT | |
| SCHEMBL20384866 | 0.59 | MAPT (0.39) | LMNARAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777111-B1 | HEAT ENDURANCE; LOW CRYSTALLINITY; EMPLOYING CONDENSED RING DERIVATIVE | KABUSHIKI KAISHA CHUO KENKYUSHO (JP) | 2004-08-17 | — | — | US | disclosed |