Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR5A2 | O00482 | 3/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25384466 | 0.69 | ALOX5AP (0.36) | ALOX5APP2RX7EPHX2HSD11B1ALDH1A1 | |
| SCHEMBL790990 | 0.68 | ALOX5AP (0.67) | ALOX5APHSD11B1 | |
| SCHEMBL25383720 | 0.67 | L3MBTL1 (0.47) | ALOX5APP2RX7EPHX2L3MBTL1MAPT | |
| SCHEMBL26667147 | 0.67 | NR5A2 (0.41) | L3MBTL1NR5A2NR5A1DDB1CRBN | |
| SCHEMBL138594 | 0.67 | EPHX2 (0.56) | P2RX7EPHX2ALDH1A1MAPTFAAH | |
| Hydrochloric Acid SCHEMBL27845477 | 0.66 | EPHX2 (0.54) | P2RX7EPHX2ALDH1A1MAPTFAAH | |
| SCHEMBL3582800 | 0.66 | ALOX5AP (0.51) | ALOX5APHSD11B1MAPT | |
| SCHEMBL11028108 | 0.66 | ALOX5AP (0.48) | ALOX5AP | |
| SCHEMBL25383742 | 0.65 | EPHX2 (0.46) | P2RX7EPHX2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL28205291 | 0.64 | EPHX2 (0.49) | P2RX7EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777111-B1 | HEAT ENDURANCE; LOW CRYSTALLINITY; EMPLOYING CONDENSED RING DERIVATIVE | KABUSHIKI KAISHA CHUO KENKYUSHO (JP) | 2004-08-17 | — | — | US | disclosed |
| US-6761747-B2 | Dispersion containing pyrogenically manufactured abrasive particles with superparamagnetic domains | DEGUSSA AG (DE) | 2004-07-13 | — | — | US | disclosed |