Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973026 | 0.71 | ALOX5 (0.42) | KDM4E | |
| SCHEMBL28534739 | 0.70 | DRD2 (0.42) | GAAALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL9192268 | 0.69 | KDM4E (0.38) | KDM4E | |
| SCHEMBL7975812 | 0.69 | SRD5A1 (0.37) | GAAMAPTKDM4ESLC18A3 | |
| SCHEMBL24105190 | 0.67 | SLC18A3 (0.41) | KDM4ESLC18A3 | |
| SCHEMBL9372709 | 0.67 | GAA (0.41) | GAAMAPTLMNAKDM4ESLC18A3 | |
| SCHEMBL20852796 | 0.64 | IDO1 (0.58) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL20852815 | 0.64 | GAA (0.46) | GAALMNAMEN1KMT2A | |
| SCHEMBL133802 | 0.64 | ALOX12 (0.68) | GAAALDH1A1MAPTLMNATDP1 | |
| SCHEMBL5453116 | 0.64 | ASPH (0.40) | ALDH1A1LMNAMEN1KMT2AALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011001931-A1 | NOVEL OXADIAZOLE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2011-01-06 | — | — | WO | disclosed |