Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6361627 | 0.89 | P2RX7 (0.60) | P2RX7KMT2AALDH1A1HDAC6TRPA1 | |
| SCHEMBL16872261 | 0.89 | P2RX7 (0.60) | P2RX7KMT2AALDH1A1HDAC6TRPA1 | |
| SCHEMBL12173045 | 0.87 | P2RX7 (0.59) | P2RX7KMT2AALDH1A1HDAC6TRPA1 | |
| SCHEMBL6848781 | 0.87 | P2RX7 (0.59) | P2RX7KMT2AALDH1A1HDAC6TRPA1 | |
| SCHEMBL6847838 | 0.87 | ERCC5 (0.53) | P2RX7ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6360839 | 0.87 | P2RX7 (0.62) | P2RX7KMT2AALDH1A1HDAC6TRPA1 | |
| SCHEMBL16950041 | 0.84 | P2RX7 (0.53) | P2RX7KMT2AALDH1A1HDAC6 | |
| SCHEMBL6849394 | 0.84 | P2RX7 (0.55) | P2RX7KMT2AALDH1A1HDAC6TRPA1 | |
| SCHEMBL6850540 | 0.81 | P2RX7 (0.50) | P2RX7KMT2AALDH1A1HDAC6 | |
| SCHEMBL2795911 | 0.81 | PPARG (0.50) | P2RX7KMT2AALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902385-B1 | DEPROTECTION METHOD FOR TETRAZOLE COMPOUND | API CORP (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-2891650-B1 | METHOD FOR PRODUCING BIARYL COMPOUND | API CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| US-9624181-B2 | Method for producing biaryl compound | API CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| US-9624181-B2 | Method for producing biaryl compound | API CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| US-9624181-B2 | Method for producing biaryl compound | API CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| US-9527821-B2 | Deprotection method for tetrazole compound | API CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-20150239854-A1 | DEPROTECTION METHOD FOR TETRAZOLE COMPOUND | API CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150239853-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | API CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150239853-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | API CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150239853-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | API CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| EP-2891650-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | API Corporation (JP) | 2015-07-08 | — | — | EP | disclosed |
| US-8530506-B2 | Process for production of biphenyl derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8530506-B2 | Process for production of biphenyl derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-8530506-B2 | Process for production of biphenyl derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| EP-2502919-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-09-26 | — | — | EP | disclosed |
| EP-2502919-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| WO-2011061996-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | 田辺三菱製薬株式会社 (JP) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239853-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | MLX, BMX, BRIX1 | P2RX7 409/4885KMT2A 1435/4885ALDH1A1 1281/4885 |
| US-20150239854-A1 | DEPROTECTION METHOD FOR TETRAZOLE COMPOUND | AGTR2, AGTR1, REN | P2RX7 864/4885KMT2A 1824/4885ALDH1A1 1137/4885 |
| US-20120232283-A1 | PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE | AGTR2, AGTR1, ACE | P2RX7 1307/4885KMT2A 1260/4885ALDH1A1 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.