SCHEMBL6848889

SCHEMBL6848889

NCC(=O)NS(=O)(=O)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 1/20 0.53
AKR1C3 P42330 1/20 0.49
BCL2L1 Q07817 2/20 0.48
MCL1 Q07820 2/20 0.48
PGR P06401 6/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ADAMTS4 O75173 1/20 0.46
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP13 P45452 1/20 0.46
MMP14 P50281 1/20 0.46
MEP1B Q16820 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.46
ADRA2C P18825 1/20 0.46
TARS1 P26639 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3928657 0.82 CA1 (0.67) KAT6AKDM4ECA1CA2MEN1
SCHEMBL6848886 0.78 MEP1B (0.56) KAT6AAKR1C3PGRKDM4EALDH1A1
SCHEMBL6850555 0.77 FBP1 (0.62) KAT6APGRCA1CA2
SCHEMBL6848795 0.77 CA1 (0.53) KAT6APGRCA1CA2KMT2A
SCHEMBL6848742 0.77 RAPGEF3 (0.59) KAT6AALDH1A1CA1CA2
SCHEMBL23676433 0.76 LARS1 (0.74) KAT6AAKR1C3PGRTARS1
SCHEMBL6850238 0.74 KAT6A (0.51) KAT6APGRKDM4ECA1CA2
SCHEMBL620147 0.74 PGR (0.60) KAT6APGR
SCHEMBL11644514 0.74 ALDH1A1 (0.73) ALDH1A1CA1CA2ADRA2C
SCHEMBL7557556 0.73 MMP1 (0.57) KAT6AKDM4EALDH1A1ADAMTS4MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6774212-B2 FOR THERAPY OF VIRAL INFECTION OR AS AN ASSAY STANDARD OR REAGENT BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-08-10 US disclosed