SCHEMBL6851297

SCHEMBL6851297

C[Si](C)(C)C#Cc1ccc(N(c2ccc(C#C[Si](C)(C)C)cc2)c2ccc(C#C[Si](C)(C)C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.33
GABRG2 P18507 3/20 0.33
GABRB3 P28472 3/20 0.33
GABRA5 P31644 3/20 0.33
GABRA3 P34903 3/20 0.33
GABRA2 P47869 3/20 0.33
GABRA4 P48169 1/20 0.31
GABRA6 Q16445 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14882956 0.92 ALDH1A1 (0.42) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL17934728 0.90 ADK (0.37) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL4107898 0.90 APP (0.41) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL12331540 0.87 CYP1A2 (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15441139 0.87 APP (0.46)
SCHEMBL10160667 0.86 CYP1A2 (0.47) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL16656240 0.86 NOS3 (0.33) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL1306384 0.85 GABRA1 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL18526935 0.84 ALDH1A1 (0.48)
SCHEMBL1098721 0.84 ALDH1A1 (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111504994-B Porphyrin-based porous organic polymer and application thereof in colorimetric detection of sulfur ions 山东省地质矿产勘查开发局第一地质大队 2022-02-18 CN disclosed
CN-111504994-A Porphyrin-based porous organic polymer and application thereof in colorimetric detection of sulfur ions 山东省地质矿产勘查开发局第一地质大队 2020-08-07 CN disclosed
US-6682782-B2 TRANSISTORS, LIQUID CRYSTAL DISPLAY, ELECTROOPTICS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2004-01-27 US disclosed
EP-1170273-B1 Alkynic compounds, their use as monomers in vacuum deposition polymerisation, thin films formed from these polymers and their use in electroluminescent devices KOREA RES INST CHEM TECH (KR) 2003-05-28 EP disclosed
EP-0950254-A4 AN ORGANIC LIGHT EMITTING DEVICE CONTAINING A PROTECTION LAYER UNIV PRINCETON (US) 2002-11-27 EP disclosed
US-20020018912-A1 Organic compound having an acetylene group, vacuum deposition polymerization thereof, deposited polymerized thin film, and electroluminescence device containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-02-14 US disclosed
EP-1170273-A1 Alkynic compounds, their use as monomers in vacuum deposition polymerisation, thin films formed from these polymers and their use in electroluminescent devices KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-01-09 EP disclosed
US-6045930-A EMISSION LAYER CONTAINING A TRIS/ETHYNIL-PHENYL/AMINE DERIVATIVE AS A RECEIVING COMPOUND THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2000-04-04 US disclosed
CN-1245581-A Organic light emitting device containing protection layer UNIV PRINCETON (US) 2000-02-23 CN disclosed
EP-0950254-A1 AN ORGANIC LIGHT EMITTING DEVICE CONTAINING A PROTECTION LAYER THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1999-10-20 EP disclosed
WO-1998028767-A9 AN ORGANIC LIGHT EMITTING DEVICE CONTAINING A PROTECTION LAYER 1998-11-05 WO disclosed
WO-1998028767-A1 AN ORGANIC LIGHT EMITTING DEVICE CONTAINING A PROTECTION LAYER THE TRUSTEES OF PRINCETON UNIVERSITY (US) 1998-07-02 WO disclosed