Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5621995 | 0.97 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2964166 | 0.78 | BRD4 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5516545 | 0.77 | ALDH1A1 (0.44) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL11470006 | 0.76 | MAPT (0.54) | ALDH1A1GAAABCG2TSHRHSD17B10 | |
| SCHEMBL17295222 | 0.76 | MAOB (0.46) | CYP19A1ABCG2CNR1SAE1UBA2 | |
| SCHEMBL5712397 | 0.75 | PRSS1 (0.46) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL5712390 | 0.75 | PRSS1 (0.46) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL6418566 | 0.75 | PRSS1 (0.46) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL1894004 | 0.75 | CA2 (0.55) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL30446884 | 0.75 | CA2 (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039199-A1 | Oxabispidine compound useful in the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039199-A1 | Oxabispidine compound useful in the treatment of cardiac arrhythmias | KCNH1, CACNA1C, CACNA1S | CA12 3633/4885CA1 1689/4885CA2 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.