Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852408 | 0.97 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2964166 | 0.80 | BRD4 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17295222 | 0.79 | MAOB (0.46) | CYP19A1CNR1CHRM1HTR2AMCHR1 | |
| SCHEMBL5516545 | 0.77 | ALDH1A1 (0.44) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL5712397 | 0.75 | PRSS1 (0.46) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL5712390 | 0.75 | PRSS1 (0.46) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL6418566 | 0.75 | PRSS1 (0.46) | CA1CA2ALDH1A1GAAABCG2 | |
| SCHEMBL1894004 | 0.75 | CA2 (0.55) | CA12CA1CA2CA9CYP19A1 | |
| SCHEMBL4326552 | 0.74 | CA2 (0.53) | CA12CA1CA2CA9CYP19A1 | |
| Hydrochloric Acid SCHEMBL9662057 | 0.74 | CA2 (0.53) | CA12CA1CA2CA9CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197519-A1 | New Process For The Preparation Of Oxabispidines | ASTRAZENECA AB (SE) | 2007-08-23 | — | — | US | disclosed |
| US-7169921-B2 | Process for the preparation of oxabispidines | ASTRAZENECA AB (SE) | 2007-01-30 | — | — | US | disclosed |
| EP-1385850-B1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2004-12-08 | — | — | EP | disclosed |
| US-20040181060-A1 | Process for the preparation of oxabispidines | ASTRAZENECA AB (SE) | 2004-09-16 | — | — | US | disclosed |
| EP-1385850-A1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | AstraZeneca AB (SE) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083690-A1 | NEW PROCESS FOR THE PREPARATION OF OXABISPIDINES | ASTRAZENECA AB (SE) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197519-A1 | New Process For The Preparation Of Oxabispidines | TST, IDH3B, INTS6 | CA12 3367/4885CA1 1773/4885CA2 3597/4885 |
| US-20040181060-A1 | Process for the preparation of oxabispidines | ADH1C, ADH1A, CYP2E1 | CA12 3843/4885CA1 1581/4885CA2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.