Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350062 | 0.87 | CES2 (0.62) | LMNAL3MBTL1CES2CES1ALOX15 | |
| SCHEMBL8967091 | 0.83 | SRD5A2 (0.61) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL9475945 | 0.83 | SRD5A2 (0.61) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL9418093 | 0.81 | TSHR (0.74) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL9418097 | 0.81 | TSHR (0.74) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL10991208 | 0.81 | HPGD (0.50) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL5322959 | 0.79 | HPGD (0.79) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL6631157 | 0.79 | CHEK2 (0.54) | HPGDLMNAL3MBTL1CES2CES1 | |
| SCHEMBL481976 | 0.76 | MAOA (0.64) | HPGDLMNAL3MBTL1CTRCTSHR | |
| SCHEMBL9476350 | 0.76 | MAOA (0.64) | HPGDLMNAL3MBTL1CTRCTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | claimed |