Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12250715 | 1.00 | MAPT (0.49) | MAPTMEN1KMT2AATMNPSR1 | |
| SCHEMBL12250729 | 1.00 | MAPT (0.49) | MAPTMEN1KMT2AATMNPSR1 | |
| SCHEMBL26880966 | 0.92 | MME (0.55) | MMEACEACE2CPA1CTSS | |
| SCHEMBL12568224 | 0.92 | MME (0.55) | MMEACEACE2CPA1CTSS | |
| SCHEMBL13550928 | 0.92 | MME (0.55) | MMEACEACE2CPA1CTSS | |
| SCHEMBL26897332 | 0.87 | LTA4H (0.55) | NPC1RAB9AMMEACEACE2 | |
| SCHEMBL1061398 | 0.86 | NPSR1 (0.55) | MAPTKMT2ANPSR1ALDH1A1MME | |
| SCHEMBL9223334 | 0.86 | NPSR1 (0.55) | MAPTKMT2ANPSR1ALDH1A1MME | |
| SCHEMBL2622217 | 0.86 | NPSR1 (0.55) | MAPTKMT2ANPSR1ALDH1A1MME | |
| SCHEMBL10061085 | 0.85 | ATM (0.43) | MAPTMEN1KMT2AATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279053-A1 | GLP-1 RECEPTOR ANTAGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-09-07 | — | — | US | disclosed |
| US-20230053449-A1 | DC-SIGN ANTIBODY DRUG CONJUGATES | NOVARTIS AG (CH) | 2023-02-23 | — | — | US | disclosed |
| US-9981008-B2 | Apolipoprotein A-I mimics | CERENIS THERAPEUTICS HOLDING SA (FR) | 2018-05-29 | — | — | US | disclosed |
| US-20180105569-A1 | ANALOGS OF GLUCAGON EXHIBITING GIP RECEPTOR ACTIVITY | UNIV INDIANA RES & TECH CORP (US) | 2018-04-19 | — | — | US | disclosed |
| US-9868772-B2 | Analogs of glucagon exhibiting GIP receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-01-16 | — | — | US | disclosed |
| US-9587005-B2 | Glucagon analogs exhibiting GIP receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-03-07 | — | — | US | disclosed |
| US-20160324923-A1 | APOLIPOPROTEIN A-I MIMICS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2016-11-10 | — | — | US | disclosed |
| US-9388232-B2 | Apolipoprotein A-I mimics | CERENIS THERAPEUTICS HOLDING SA (FR) | 2016-07-12 | — | — | US | disclosed |
| US-20160158375-A1 | DIPEPTIDE LINKED MEDICINAL AGENTS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2016-06-09 | — | — | US | disclosed |
| US-9340600-B2 | Glucagon analogs exhibiting GIP receptor activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-05-17 | — | — | US | disclosed |
| US-20130137849-A1 | DIPEPTIDE LINKED MEDICINAL AGENTS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-30 | — | — | US | disclosed |
| US-20130123462-A1 | AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130116173-A1 | Glucagon Analogs Exhibiting GIP Receptor Activity | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-05-09 | — | — | US | disclosed |
| US-8378068-B2 | Apolipoprotein A-I mimics | CERENIS THERAPEUTICS HOLDING SA (FR) | 2013-02-19 | — | — | US | disclosed |
| US-20120238493-A1 | GLUCAGON ANALOGS EXHIBITING GIP RECEPTOR ACTIVITY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2012-09-20 | — | — | US | disclosed |
| US-20120021982-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION | INSTITUT DE CARDIOLOGIE DE MONTREAL (CA) | 2012-01-26 | — | — | US | disclosed |
| US-20110288003-A1 | AMIDE BASED GLUCAGON AND SUPERFAMILY PEPTIDE PRODRUGS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110237493-A1 | DIPEPTIDE LINKED MEDICINAL AGENTS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2011-09-29 | — | — | US | disclosed |
| US-20100267631-A1 | APOLIPOPROTEIN A-I MIMICS | CERENIS THERAPEUTICS HOLDING SA (FR) | 2010-10-21 | — | — | US | disclosed |
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137849-A1 | DIPEPTIDE LINKED MEDICINAL AGENTS | DNPEP, PEPD, CNDP2 | MAPT 2884/4885MEN1 1171/4885KMT2A 2937/4885 |
| US-20130123462-A1 | AMIDE BASED GLUCAGON SUPERFAMILY PEPTIDE PRODRUGS | GCG, GLP1R, IAPP | MAPT 4540/4885MEN1 1548/4885KMT2A 2674/4885 |
| US-20120238493-A1 | GLUCAGON ANALOGS EXHIBITING GIP RECEPTOR ACTIVITY | GLP1R, GIPR, GCGR | MAPT 4870/4885MEN1 1995/4885KMT2A 4089/4885 |
| US-20230279053-A1 | GLP-1 RECEPTOR ANTAGONISTS | GLP1R, GIPR, GCGR | MAPT 4607/4885MEN1 1495/4885KMT2A 2832/4885 |
| US-20100267631-A1 | APOLIPOPROTEIN A-I MIMICS | APOB, APOL1, LIPG | MAPT 1465/4885MEN1 1235/4885KMT2A 4479/4885 |
| US-20230053449-A1 | DC-SIGN ANTIBODY DRUG CONJUGATES | DCUN1D4, CD14, DCUN1D3 | MAPT 1439/4885MEN1 2029/4885KMT2A 2403/4885 |
| US-20180105569-A1 | ANALOGS OF GLUCAGON EXHIBITING GIP RECEPTOR ACTIVITY | GLP1R, GIPR, GCGR | MAPT 4872/4885MEN1 2040/4885KMT2A 3839/4885 |
| US-20160158375-A1 | DIPEPTIDE LINKED MEDICINAL AGENTS | DNPEP, PEPD, CNDP2 | MAPT 2884/4885MEN1 1171/4885KMT2A 2937/4885 |
| US-20110288003-A1 | AMIDE BASED GLUCAGON AND SUPERFAMILY PEPTIDE PRODRUGS | GCG, GLP1R, IAPP | MAPT 4612/4885MEN1 1543/4885KMT2A 2871/4885 |
| US-20160324923-A1 | APOLIPOPROTEIN A-I MIMICS | APOB, APOL1, LIPG | MAPT 1465/4885MEN1 1235/4885KMT2A 4479/4885 |
| US-20120021982-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF LEFT VENTRICULAR DIASTOLIC DYSFUNCTION | APOB, FABP3, TNNT2 | MAPT 1865/4885MEN1 4730/4885KMT2A 4755/4885 |
| US-20130116173-A1 | Glucagon Analogs Exhibiting GIP Receptor Activity | GLP1R, GIPR, GCGR | MAPT 4870/4885MEN1 1995/4885KMT2A 4089/4885 |
| US-20110237493-A1 | DIPEPTIDE LINKED MEDICINAL AGENTS | DNPEP, PEPD, CNDP2 | MAPT 2884/4885MEN1 1171/4885KMT2A 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.