SCHEMBL685586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4260137	0.93	TRPA1 (0.49)	ALDH1A1TRPA1GAAKDM4EKMT2A
	SCHEMBL6198028	0.90	ALDH1A1 (0.51)	ALDH1A1TRPA1TACR2AMY1AGAA
	SCHEMBL31619156	0.90	ALDH1A1 (0.51)	ALDH1A1TRPA1TACR2AMY1AGAA
	SCHEMBL685660	0.87	TRPA1 (0.54)	ALDH1A1TRPA1GAAKDM4EKMT2A
	SCHEMBL685022	0.85	FDPS (0.41)	ALDH1A1TRPA1KDM4EHDAC3HDAC4
	SCHEMBL6215450	0.85	TRPA1 (0.56)	ALDH1A1TRPA1AMY1AGAAKDM4E
	SCHEMBL13210789	0.85	TRPA1 (0.56)	ALDH1A1TRPA1AMY1AGAAKDM4E
	SCHEMBL2679839	0.84	ALDH1A1 (0.62)	ALDH1A1TACR2GAAKDM4EKMT2A
	SCHEMBL685024	0.84	SMPD1 (0.40)	ALDH1A1TRPA1KDM4EHDAC3HDAC4
	SCHEMBL16962089	0.82	KMT2A (0.49)	ALDH1A1TACR2GAAKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.