Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856809 | 0.89 | MTNR1A (0.36) | MTNR1AMTNR1BABL1APPCASP3 | |
| SCHEMBL6856506 | 0.84 | ANO1 (0.41) | PDK1PDK2PDK3PDK4ABL1 | |
| SCHEMBL6857370 | 0.80 | TRPV1 (0.39) | PDK1PDK2PDK3PDK4ABL1 | |
| SCHEMBL6855696 | 0.79 | AXL (0.45) | KDM4EALDH1A1 | |
| SCHEMBL6857381 | 0.73 | MDM2 (0.40) | ABL1TRPV1BACE1 | |
| SCHEMBL6856769 | 0.72 | KMO (0.39) | CASP3TSPOKDM4EMEN1ALDH1A1 | |
| SCHEMBL6857380 | 0.69 | TRPV1 (0.38) | ABL1TRPV1KDM4E | |
| SCHEMBL6857409 | 0.69 | AVPR1B (0.43) | BACE1MEN1KMT2A | |
| SCHEMBL6856237 | 0.68 | KMO (0.42) | TSPOKMO | |
| SCHEMBL6856761 | 0.68 | AVPR1B (0.41) | EGFRTRPV1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |