Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19630458 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1905868 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3967600 | 0.78 | CA1 (0.38) | SMN1; SMN2POLBCA2CA14CA12 | |
| SCHEMBL4742935 | 0.77 | CA2 (0.37) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13787269 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL2001127 | 0.77 | MEN1 (0.59) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13561305 | 0.76 | CA12 (0.34) | SMN1; SMN2ALDH1A1CA2CA14CA12 | |
| SCHEMBL3884426 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL28342065 | 0.76 | KDM4E (0.33) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL16307350 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260262-B | Cytosine azide Process for the preparation of compounds | 深圳赛陆医疗科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118084996-A | Reversible termination nucleotide and application thereof in DNA synthesis sequencing and single molecule sequencing | 上海交通大学 | 2024-05-28 | — | — | CN | claimed |
| US-11001886-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | AGILENT TECHNOLOGIES, INC. (US) | 2021-05-11 | — | — | US | claimed |
| US-20190127790-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2019-05-02 | — | — | US | claimed |
| CN-103804447-B | Aza guanosine and synthetic method thereof and the purposes in DNA sequencing | 上海交通大学 | 2016-08-17 | — | — | CN | claimed |
| CN-103601779-B | The synthetic method of 7-denitrification-2 '-deoxidation-7-halogen 9 substituted guanine nucleosides | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2016-05-04 | — | — | CN | claimed |
| CN-103819523-A | Method for synthesizing 7-denitrification-7-halogen guanosine | UNIV SHANGHAI JIAOTONG | 2014-05-28 | — | — | CN | claimed |
| CN-103804447-A | Hybrid azaguanosine as well as synthesis method and application thereof in DNA sequencing | UNIV SHANGHAI JIAOTONG | 2014-05-21 | — | — | CN | claimed |
| CN-103601778-A | Synthetic method of 7-denitrified-7-substituted guanosine | UNIV SHANGHAI JIAOTONG | 2014-02-26 | — | — | CN | claimed |
| CN-103601779-A | Synthetic method of 7-denitrified-2'-deoxidized-7-halogen substituted guanosine | UNIV SHANGHAI JIAOTONG | 2014-02-26 | — | — | CN | claimed |
| US-8536323-B2 | Modified nucleotides | PIERCE BIOTECHNOLOGY, INC. (US) | 2013-09-17 | — | — | US | claimed |
| US-20110262917-A1 | MODIFIED NUCLEOTIDES | PIERCE BIOTECHNOLOGY, INC. (US) | 2011-10-27 | — | — | US | claimed |
| EP-0251786-B1 | Alkynylamino-nucleotides | DU PONT (US) | 1994-11-30 | — | — | EP | claimed |
| US-5047519-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-10 | — | — | US | claimed |
| EP-0251786-A2 | Alkynylamino-nucleotides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-07 | — | — | EP | claimed |
| JP-7316174-A | — | — | None | — | — | JP | disclosed |
| JP-5148225-A | — | — | None | — | — | JP | disclosed |
| EP-0309969-A2 | Method of gene mapping | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0252683-A2 | Process and reagents for DNA sequence analysis | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0251786-A2 | Alkynylamino-nucleotides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127790-A1 | 3'-OH UNBLOCKED, FAST PHOTOCLEAVABLE TERMINATING NUCLEOTIDES AND METHODS FOR NUCLEIC ACID SEQUENCING | RNGTT, NT5C3B, NSUN2 | SMN1; SMN2 3089/4885ALDH1A1 2244/4885POLB 5/4885 |
| US-11001886-B2 | 3′-OH unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing | RNGTT, NT5C3B, NSUN2 | SMN1; SMN2 3118/4885ALDH1A1 2163/4885POLB 5/4885 |
| US-20110262917-A1 | MODIFIED NUCLEOTIDES | NUDT1, RNMT, RNGTT | SMN1; SMN2 3322/4885ALDH1A1 2422/4885POLB 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.