Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862518 | 0.81 | TP53 (0.76) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL6860844 | 0.70 | CYP2C19 (0.43) | MAPTTP53POLBLMNASMN1; SMN2 | |
| SCHEMBL6862770 | 0.68 | SMN1; SMN2 (0.39) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL15485025 | 0.68 | LMNA (0.63) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL6860475 | 0.67 | LMNA (0.44) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL6861396 | 0.67 | MAPT (0.54) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL15492960 | 0.67 | TRPM2 (0.47) | MAPTPOLBLMNATSHRSMN1; SMN2 | |
| SCHEMBL6861342 | 0.66 | GRIA2 (0.54) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL1006583 | 0.66 | MAPT (0.81) | MAPTTP53POLBLMNATSHR | |
| SCHEMBL13753903 | 0.66 | LMNA (1.00) | MAPTLMNATSHRRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011036889-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2011-03-31 | — | — | WO | disclosed |