SCHEMBL6864700

SCHEMBL6864700

Cc1ccc(C(=O)Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 2/20 0.62
ACR P10323 2/20 0.62
TP53 P04637 1/20 0.58
MAPT P10636 2/20 0.54
ALDH1A1 P00352 3/20 0.53
CYP2A6 P11509 1/20 0.53
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 1/20 0.52
HIF1A Q16665 1/20 0.52
PARP15 Q460N3 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
F2 P00734 1/20 0.50
KMT2A Q03164 5/20 0.49
MEN1 O00255 1/20 0.49
POLB P06746 1/20 0.49
LMNA P02545 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
GBA1 P04062 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11709820 1.00 PRSS1 (0.62) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL12736311 0.95 TP53 (0.61) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL91884 0.95 TP53 (0.61) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL13384914 0.95 TP53 (0.61) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL8496209 0.91 ALDH1A1 (0.58) PRSS1ACRMAPTALDH1A1CYP1A2
SCHEMBL29038955 0.91 ALDH1A1 (0.58) PRSS1ACRMAPTALDH1A1CYP1A2
SCHEMBL15119047 0.89 RAB9A (0.64) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL21676944 0.88 PRSS1 (0.53) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL103902 0.87 ALDH1A1 (0.53) PRSS1ACRTP53MAPTALDH1A1
SCHEMBL8074037 0.87 CYP1A2 (0.58) PRSS1ACRMAPTALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-20230339238-A1 IMAGE RECORDING METHOD AND INK JET-RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
US-11667840-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
US-11667840-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
EP-3433236-B1 CYANOPYRIMIDINE DERIVATIVES SUITABLE AS COMPONENTS IN LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2021-10-27 EP disclosed
EP-3248061-B1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-10-14 EP disclosed
EP-3529331-B1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-10-07 EP disclosed
EP-3248060-B1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-09-02 EP disclosed
US-20200262795-A1 CYANOPYRIMIDINE DERIVATIVES MERCK PATENT GMBH (DE) 2020-08-20 US disclosed
US-20200255739-A1 LIGHT MODULATION ELEMENT MERCK PATENT GMBH (DE) 2020-08-13 US disclosed
US-20080226888-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-09-18 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080129934-A1 OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY KONICA MINOLTA OPTO, INC. (JP) 2008-06-05 US disclosed
US-20070190268-A1 Optical film and optical compensatory film, polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-08-16 US disclosed
US-20070081115-A1 Polarizing plate and image display device using the same FUJIFILM CORPORATION (JP) 2007-04-12 US disclosed
US-6809206-B2 CONTACTING A PHENYL ESTER COMPOUND WITH A CYCLIC COMPOUND IN THE PRESENCE OF A SOURCE OF CYANIDE OR FLUORIDE TO PREPARE ACYLATED CYCLIC 1,3-DICARBONYL COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY 2004-10-26 US disclosed
US-20030232984-A1 Method for acylating cyclic compounds E. I. DU PONT DE NEMOURS AND COMPANY 2003-12-18 US disclosed
US-20020049317-A1 Method for acylating cyclic compounds E.I. DU PONT DE NEMOURS AND COMPANY 2002-04-25 US disclosed
US-4444844-A LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY RICOH CO., LTD. (JP) 1984-04-24 US disclosed
US-3983049-A Liquid crystal compositions with positive dielectric anisotropy GENERAL ELECTRIC COMPANY (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049317-A1 Method for acylating cyclic compounds LCAT, ACOT7, AGPAT5 PRSS1 3894/4885ACR 24/4885TP53 4266/4885
US-11858952-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 PRSS1 3964/4885ACR 2726/4885TP53 3578/4885
US-20030232984-A1 Method for acylating cyclic compounds LCAT, ACOT7, AGPAT5 PRSS1 3894/4885ACR 24/4885TP53 4266/4885
US-11667840-B2 Liquid-crystalline medium FES, BLM, CXCL12 PRSS1 1867/4885ACR 1436/4885TP53 832/4885
US-20200262795-A1 CYANOPYRIMIDINE DERIVATIVES MCM6, MCM4, MCM2 PRSS1 4050/4885ACR 3986/4885TP53 925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.