Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | RORA | P35398 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | RORB | Q92753 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667530 | 0.81 | CA1 (0.47) | CA1LMNAALDH1A1CA12CA2 | |
| SCHEMBL11580208 | 0.78 | TAS2R14 (0.38) | TAS2R14CA1LMNAALDH1A1NPSR1 | |
| SCHEMBL777136 | 0.72 | MMP1 (0.38) | CA1CA12CA2MMP3CA9 | |
| SCHEMBL19707140 | 0.72 | CA1 (0.31) | CA1CA12CA2CA9 | |
| SCHEMBL6546529 | 0.72 | TAS2R14 (0.31) | TAS2R14LMNA | |
| SCHEMBL26503794 | 0.72 | RORC (0.36) | TAS2R14LMNAALDH1A1SMN1; SMN2RORC | |
| SCHEMBL10312295 | 0.70 | PER2 (0.45) | TAS2R14CA1LMNAALDH1A1NPSR1 | |
| SCHEMBL28163257 | 0.70 | CA1 (0.60) | CA1LMNAALDH1A1NPSR1CA12 | |
| SCHEMBL14229123 | 0.70 | CNR2 (0.40) | TAS2R14CA1LMNAALDH1A1NPSR1 | |
| SCHEMBL14229124 | 0.70 | MMP3 (0.36) | TAS2R14CA1CA12CA2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093352-A1 | THIAZOLE DERIVATIVE | 武田薬品工業株式会社 (JP) | 2011-08-04 | — | — | WO | disclosed |
| US-7449447-B2 | Peptidomimetic NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2008-11-11 | — | — | US | disclosed |