Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728216 | 0.81 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2ACA2CA9 | |
| SCHEMBL5857980 | 0.72 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ACA2CA9 | |
| SCHEMBL28498842 | 0.72 | ALDH1A1 (0.39) | MEN1ALDH1A1KMT2ACA2CA9 | |
| SCHEMBL758883 | 0.71 | CA2 (0.41) | ALDH1A1CA2CA1L3MBTL1 | |
| SCHEMBL160 | 0.71 | CA2 (0.41) | ALDH1A1CA2CA1L3MBTL1 | |
| SCHEMBL758884 | 0.71 | CA2 (0.41) | ALDH1A1CA2CA1L3MBTL1 | |
| Triphenylphosphine Oxide SCHEMBL1597562 | 0.71 | LMNA (0.39) | MEN1ALDH1A1KMT2ACA2CA9 | |
| Triphenylphosphine Oxide SCHEMBL2865423 | 0.71 | LMNA (0.39) | MEN1ALDH1A1KMT2ACA2CA9 | |
| SCHEMBL8847449 | 0.69 | HTR6 (0.42) | ALDH1A1KMT2ACA2CA9CA1 | |
| SCHEMBL37033 | 0.69 | HTR6 (0.42) | ALDH1A1CA2CA9CA1CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394147-A1 | CARBOXYLIC ACID DERIVATIVE AND MEDICINE COMPRISING SALT OR ESTER OF THE SAME | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |