Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1361112 | 0.75 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL6867409 | 0.71 | — | — | |
| SCHEMBL5051725 | 0.63 | MEN1 (0.37) | MEN1KMT2AKDM4E | |
| SCHEMBL3137075 | 0.63 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL1072568 | 0.56 | KDM4E (0.45) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL13785535 | 0.56 | KDM4E (0.40) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL10798452 | 0.55 | KDM4E (0.50) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL14950267 | 0.52 | ALDH1A1 (0.50) | KDM4EALDH1A1LMNA | |
| SCHEMBL10298155 | 0.52 | KDM4E (0.36) | KDM4EALDH1A1LMNA | |
| SCHEMBL8398977 | 0.51 | KDM4E (0.45) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069123-B1 | PROCESS FOR PRODUCING BENZOTHIOPHENECARBOXYLIC ACID AMIDE DERIVATIVES | SHIONOGI & CO (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-20020161242-A1 | Process for preparing benzothiophenecarboxamide derivatives | HONMA TSUNETOSHI (JP) | 2002-10-31 | — | — | US | disclosed |
| US-20020156297-A1 | Process for preparing benzothiophenecarboxamide derivatives | OKADA TETSUO (JP) | 2002-10-24 | — | — | US | disclosed |
| US-6465662-B1 | OXIDIZING 2-HYDROXYETHYL-10 NORPINAN-3-YL)-2-AMINE AMIDES OF OXY-SUBSTITUTED BENZOTHIOPHENECARBOXYLIC ACIDS TO FORM ALDEHYDES IN THE PRESENCE OF 2,2,6,6-TETRAMETHYLPIPERIDINE-1-OXYLS. | SHIONOGI & CO., LTD. (JP) | 2002-10-15 | — | — | US | disclosed |
| US-6462241-B2 | REACTING AN AMINO ALCOHOL WITH A BENZOTHIOPHENE, REACTING THE PRODUCT WITH A HALO OXACID IN THE PRESENCE OF 2,2,6,6-TETRA METHYLPIPERIDINE-1-OXYLS, FURTHER REACTING WITH AN YLIDE UNDER WITTIG REACTION CONDITIONS AND DEPROTECTING | SHIONOGI & CO., LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| US-20020115871-A1 | Process for preparing benzothiophenecarboxamide derivatives | OKADA TETSUO (JP) | 2002-08-22 | — | — | US | disclosed |
| US-6399788-B1 | AMIDATION | SHIONOGI & CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-1069123-A1 | PROCESS FOR PRODUCING BENZOTHIOPHENECARBOXYLIC ACID AMIDE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161242-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | MEN1 4227/4885KMT2A 1417/4885KDM4E 1943/4885 |
| US-20020156297-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | MEN1 4227/4885KMT2A 1417/4885KDM4E 1943/4885 |
| US-20020115871-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | MEN1 4227/4885KMT2A 1417/4885KDM4E 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.