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Arginine

Arginine

SCHEMBL6868910

CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)OC(=O)[C@@H](N)C(C)C.CC(C)C[C@H](N)C(=O)OC[C@H](N)C(=O)O.CC(C)C[C@H](N)C(=O)OC[C@H](N)C(=O)OC[C@H](N)C(=O)Oc1ccc(C[C@H](N)C(=O)O)cc1.CC(C)[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.C[C@H](N)C(=O)OC(=O)CN.C[C@H](N)C(=O)OC(=O)[C@@H]1CCCN1.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCC(=O)O.NCC(=O)O.N[C@@H](COC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ APLNR P35414 2/20 0.33
▸ GLP1R P43220 9/20 0.32
▸ VIPR1 P32241 4/20 0.31
▸ VIPR2 P41587 3/20 0.31
▸ GHSR Q92847 2/20 0.31
▸ KLK7 P49862 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL7575372 0.86 TUBB4A (0.34) APLNRGLP1RKLK7
Arginine SCHEMBL7211146 0.86 GLP1R (0.35) APLNRGLP1RVIPR1VIPR2
Arginine SCHEMBL8152157 0.84 GLP1R (0.38) GLP1R
Phenylalanine SCHEMBL8314461 0.84 APLNR (0.33) APLNRGLP1R
Tyrosine SCHEMBL6253682 0.84 REN (0.31) —
Arginine SCHEMBL8311754 0.83 TUBB4A (0.33) APLNRKLK7
Tryptophan SCHEMBL9295342 0.83 PTH1R (0.40) GLP1R
Histidine SCHEMBL3663298 0.83 REN (0.33) —
Phenylalanine SCHEMBL1585346 0.82 TUBB4A (0.33) GLP1RKLK7
Tryptophan SCHEMBL5820703 0.82 PTH1R (0.39) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1445325-A1 PROCESSES FOR PRODUCING ISOMALTOSE AND ISOMALTITOL AND USE THEREOF Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) 2004-08-11 — — EP disclosed