Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.32 |
| ▸ | TUBB | P07437 | 4/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 8/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031168 | 0.87 | ACR (0.49) | ACRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5027206 | 0.86 | ACR (0.44) | ACRLMNACYP1A2HIF1ASMN1; SMN2 | |
| SCHEMBL5928370 | 0.85 | ACR (0.42) | ACRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8517147 | 0.82 | ACR (0.54) | ACRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7945958 | 0.80 | RORC (0.35) | RORC | |
| SCHEMBL6101123 | 0.79 | CYP3A4 (0.37) | LMNASMN1; SMN2RORCMAPK1MEN1 | |
| SCHEMBL7765077 | 0.78 | MMP2 (0.41) | LMNARORCMEN1KMT2AHTT | |
| SCHEMBL5689205 | 0.78 | KEAP1 (0.40) | LMNARORCMEN1KMT2AHTT | |
| SCHEMBL5031175 | 0.77 | SPPL2A (0.37) | KMT2A | |
| SCHEMBL5026552 | 0.74 | RORC (0.36) | ACRRORCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052250-B1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-0813519-B1 | SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | SEARLE & CO (US) | 2001-05-09 | — | — | EP | disclosed |
| US-6169085-B1 | A VIRICIDE FOR PREVENTING AND TREATING RETROVIRAL INFECTION OR THE SPREAD OF A RETROVIRUS, INHIBITING REPLICATION OF A RETROVIRUS AND TREATING AIDS | G. D. SEARLE & COMPANY | 2001-01-02 | — | — | US | disclosed |
| EP-1052250-A1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 2000-11-15 | — | — | EP | disclosed |