Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.39 |
| ▸ | TUBB | P07437 | 4/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031168 | 0.86 | ACR (0.49) | ACRLMNACYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL7609854 | 0.83 | RORC (0.39) | ACRKMT2ARORC | |
| SCHEMBL6869361 | 0.82 | ACR (0.44) | ACRLMNACYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL5027206 | 0.81 | ACR (0.44) | ACRLMNACYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL5928370 | 0.78 | ACR (0.42) | ACRLMNACYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL8370885 | 0.76 | ACR (0.43) | ACRLMNACYP1A2SMN1; SMN2HIF1A | |
| SCHEMBL7452491 | 0.73 | KEAP1 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7450471 | 0.73 | RORC (0.39) | LMNAALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL7450627 | 0.72 | RORC (0.46) | RORC | |
| SCHEMBL5172918 | 0.72 | ACR (0.56) | ACRLMNACYP1A2SMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999059989-A1 | PROCESS FOR THE PREPARATION OF A BENZO FUSED HETEROCYCLO SULFONYL HALIDE INTERMEDIATE | G.D. SEARLE & CO. (US) | 1999-11-25 | — | — | WO | disclosed |